opensourcestartups

> /v1/language/python

Best open source Python projects[100]

100 curated open source projects written primarily in Python, ranked by GitHub stars. Combined: 2,818,207 stars.

// AI & ML№ 001
AutoGPT

AutoGPT

PYTHON

AutoGPT is the vision of accessible AI for everyone

★ STARS

184.1k

⑂ FORKS

44.5k

OPEN PROJECT
// AI & ML№ 002
Stable Diffusion WebUI

Stable Diffusion WebUI

PYTHON

Stable Diffusion web UI

★ STARS

162.8k

⑂ FORKS

26.2k

OPEN PROJECT
// AI & ML№ 003
Hugging Face Transformers

Hugging Face Transformers

PYTHON

State-of-the-art Machine Learning for PyTorch, TensorFlow, and JAX

★ STARS

160.4k

⑂ FORKS

26.5k

OPEN PROJECT
// DEVELOPER TOOLS№ 004
Langflow

Langflow

★ FEATUREDPYTHON

Visual builder for AI-powered applications

★ STARS

147.8k

⑂ FORKS

8.9k

OPEN PROJECT
// AI & ML№ 005
LangChain

LangChain

★ FEATUREDPYTHON

Build context-aware reasoning applications

★ STARS

136.1k

⑂ FORKS

14.8k

OPEN PROJECT
// AI & ML№ 006
Open WebUI

Open WebUI

★ FEATUREDPYTHON

Extensible, self-hosted AI interface for workflow

★ STARS

136.1k

⑂ FORKS

19.4k

OPEN PROJECT
// WEB FRAMEWORK№ 007
FastAPI

FastAPI

PYTHON

FastAPI framework, high performance, easy to learn, fast to code, ready for production

★ STARS

98.0k

⑂ FORKS

6.6k

OPEN PROJECT
// DEVELOPER TOOLS№ 008
Browser Use

Browser Use

★ FEATUREDPYTHON

Leading open-source web agent project with 50k stars in 3 months

★ STARS

92.9k

⑂ FORKS

10.5k

OPEN PROJECT
// DEVELOPER TOOLS№ 009
Home Assistant

Home Assistant

★ FEATUREDPYTHON

Local control smart home with privacy first

★ STARS

87.0k

⑂ FORKS

37.4k

OPEN PROJECT
// AI & ML№ 010
OpenHands

OpenHands

★ FEATUREDPYTHON

Build and deploy autonomous coding agents at scale with model-agnostic, secure platform. Automate code reviews, testing, documentation, and complex refactoring tasks.

★ STARS

72.9k

⑂ FORKS

9.2k

OPEN PROJECT
// AI & ML№ 011
OpenBB

OpenBB

★ FEATUREDPYTHON

Integrate, visualize, and analyze data in one place with OpenBB's AI-driven platform for financial research and analytics.

★ STARS

67.2k

⑂ FORKS

6.7k

OPEN PROJECT
// DEVELOPER TOOLS№ 012
Crawl4AI

Crawl4AI

★ FEATUREDPYTHON

Open-source web crawler optimized for AI/LLMs

★ STARS

65.2k

⑂ FORKS

6.7k

OPEN PROJECT
// AI & ML№ 013
Unsloth AI

Unsloth AI

★ FEATUREDPYTHON

Open-Source Reinforcement Learning (RL) & Fine-tuning for LLMs.

★ STARS

63.8k

⑂ FORKS

5.6k

OPEN PROJECT
// AI & ML№ 014
Open Interpreter

Open Interpreter

PYTHON

A natural language interface for computers

★ STARS

63.4k

⑂ FORKS

4.8k

OPEN PROJECT
// AI & ML№ 015
PrivateGPT

PrivateGPT

PYTHON

Interact with your documents using LLMs, privately

★ STARS

57.2k

⑂ FORKS

7.4k

OPEN PROJECT
// AI & ML№ 016
Mem0

Mem0

★ FEATUREDPYTHON

The Memory layer for your AI apps

★ STARS

55.1k

⑂ FORKS

6.2k

OPEN PROJECT
// OTHER№ 017
Odoo

Odoo

★ FEATUREDPYTHON

Comprehensive ERP solution offering integrated modules for finance, HR, sales, inventory, and more, tailored for businesses of all sizes.

★ STARS

50.5k

⑂ FORKS

32.3k

OPEN PROJECT
// AI & ML№ 018
LlamaIndex

LlamaIndex

PYTHON

LlamaIndex is a data framework for LLM-based applications

★ STARS

49.2k

⑂ FORKS

5.2k

OPEN PROJECT
// AI & ML№ 019
LiteLLM

LiteLLM

★ FEATUREDPYTHON

Call every LLM API like it's OpenAI [100+ LLMs]

★ STARS

46.2k

⑂ FORKS

7.9k

OPEN PROJECT
// AI & ML№ 020
Aider

Aider

★ FEATUREDPYTHON

A terminal-based coding assistant that helps you write, modify and understand code through natural language conversations with AI models

★ STARS

44.5k

⑂ FORKS

4.4k

OPEN PROJECT
// DEVOPS№ 021
Sentry

Sentry

★ FEATUREDPYTHON

Detect, diagnose, and resolve software issues quickly with powerful error tracking, performance monitoring, and release management.

★ STARS

43.8k

⑂ FORKS

4.7k

OPEN PROJECT
// OTHER№ 022
Paperless-home

Paperless-home

★ FEATUREDPYTHON

A powerful open-source solution for managing, organizing, and searching your digital documents with ease and efficiency.

★ STARS

40.4k

⑂ FORKS

2.6k

OPEN PROJECT
// AI & ML№ 023
Agno

Agno

★ FEATUREDPYTHON

Open-source platform that enables developers to create, deploy and monitor AI agents with built-in memory, knowledge integration, and external tool connectivity.

★ STARS

40.0k

⑂ FORKS

5.4k

OPEN PROJECT
// AI & ML№ 024
MindsDB

MindsDB

★ FEATUREDPYTHON

Connect, Unify, Respond to any data, anywhere with human-level…

★ STARS

39.1k

⑂ FORKS

6.2k

OPEN PROJECT
// AI & ML№ 025
Khoj

Khoj

★ FEATUREDPYTHON

AI for humans

★ STARS

34.4k

⑂ FORKS

2.2k

OPEN PROJECT
// ANALYTICS№ 026
PostHog

PostHog

PYTHON

Open-source product analytics, session recording, feature flagging and A/B testing

★ STARS

34.4k

⑂ FORKS

2.7k

OPEN PROJECT
// AI & ML№ 027
Pythagora

Pythagora

★ FEATUREDPYTHON

A VS Code extension that uses AI to help developers plan, write, test, and deploy full-stack web applications with minimal coding required.

★ STARS

33.8k

⑂ FORKS

3.5k

OPEN PROJECT
// OTHER№ 028
ERPNext

ERPNext

★ FEATUREDPYTHON

Open-source ERP solution offering modules for accounting, inventory, HR, CRM, and more. Customizable and scalable for businesses of all sizes.

★ STARS

33.7k

⑂ FORKS

11.2k

OPEN PROJECT
// OTHER№ 029
Kitty

Kitty

★ FEATUREDPYTHON

High-performance terminal emulator with GPU acceleration, graphics support, and advanced scripting capabilities for developers and system administrators.

★ STARS

32.8k

⑂ FORKS

1.4k

OPEN PROJECT
// DATABASE№ 030
JumpServer

JumpServer

★ FEATUREDPYTHON

Open-source privileged access management solution offering secure, browser-based access to SSH, RDP, Kubernetes, databases and remote applications.

★ STARS

30.4k

⑂ FORKS

5.7k

OPEN PROJECT

// FREQUENTLY ASKED

What are the best open source Python projects?

The most popular by GitHub stars are AutoGPT, Stable Diffusion WebUI, Hugging Face Transformers, Langflow, LangChain — see all 100 above.

What is the most popular Python project?

AutoGPT (184,089 stars). AutoGPT is the vision of accessible AI for everyone

How is this list updated?

Star counts and project metadata are refreshed nightly from the GitHub API.